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Papers of the Week

2020 Oct

Clin Gastroenterol Hepatol



Effects of Apremilast, an Oral Inhibitor of Phosphodiesterase 4, in a Randomized Trial of Patients With Active Ulcerative Colitis.


Danese S, Neurath MF, Kopoń A, Zakko SF, Simmons TC, Fogel R, Siegel CA, Panaccione R, Zhan X, Usiskin K, Chitkara D
Clin Gastroenterol Hepatol. 2020 Oct; 18(11):2526-2534.e9.
PMID: 31926340.


New oral therapeutic agents are needed for patients with ulcerative colitis (UC) who are unresponsive or intolerant to conventional therapy.