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Papers of the Week

Papers: 4 Jan 2020 - 10 Jan 2020

Human Studies, Pharmacology/Drug Development


2020 03

Pediatr Neurol


Intranasal Ketamine for Abortive Migraine Therapy in Pediatric Patients: A Single-Center Review.


Turner AL, Shandley S, Miller E, Perry SM, Ryals B
Pediatr Neurol. 2020 03; 104:46-53.
PMID: 31902550.


Ketamine has recently emerged as a promising therapeutic alternative for abortive migraine therapy, likely secondary to N-methyl-d-aspartate antagonism. Most reports examine adults and the intravenous route. Fewer utilize intranasal administration or pediatric populations. Given the limited evidence for intranasal ketamine in pediatric migraine populations, we retrospectively reviewed our experience to further characterize safety and efficacy of intranasal ketamine in this population.