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Papers of the Week

2020 May

Orthod Craniofac Res



Maternal Related Factors in the Origin of Isolated Cleft Palate – a Population-based Case-control Study.


Ács L, Bányai D, Nemes B, Nagy K, Ács N, Bánhidy F, Rózsa N
Orthod Craniofac Res. 2020 May; 23(2):174-180.
PMID: 31854100.


Isolated cleft palate (CPO) is the rarest form of oral clefting affecting 1 to 25 per 10,000 newborns worldwide. There is increasing evidence for the different pathogenetic backgrounds of CPO and cleft lip with or without cleft palate. The role of environmental factors in the origin of nonsyndromic and syndromic CPO is unclear in most patients. The aim of this study was to estimate possible maternal risk factors in the origin of CPO.