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Papers of the Week

2020 Apr

Support Care Cancer



What is the evidence for mirtazapine in treating cancer-related symptomatology? A systematic review.


Economos G, Lovell N, Johnston A, Higginson IJ
Support Care Cancer. 2020 Apr; 28(4):1597-1606.
PMID: 31858251.


Cancer patients often experience multiple distressing symptoms which are challenging to manage. It would therefore be helpful to find a treatment that alleviates more than one symptom, to avoid polypharmacy: mirtazapine has been used in several studies for this purpose. The objective of this study was to assess the effectiveness and safety of mirtazapine in alleviating one or more frequently encountered cancer-related symptoms.