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Papers of the Week

Papers: 14 Dec 2019 - 20 Dec 2019

Pharmacology/Drug Development

2020 Mar

Pharmacoepidemiol Drug Saf



Long-term opioid therapy definitions and predictors: A systematic review.


Karmali RN, Bush C, Raman SR, Campbell CI, Skinner AC, Roberts AW
Pharmacoepidemiol Drug Saf. 2020 Mar; 29(3):252-269.
PMID: 31851773.


This review sought to (a) describe definitions of long-term opioid therapy (LTOT) outcome measures, and (b) identify the predictors associated with the transition from short-term opioid use to LTOT for opioid-naïve individuals.