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Papers of the Week

Papers: 7 Dec 2019 - 13 Dec 2019

2020 Aug

J Clin Epidemiol


Reviews may overestimate the effectiveness of medicines for back pain: systematic review and meta-analysis.


Bagg MK, O'Hagan E, Zahara P, Wand BM, Hübscher M, Moseley LG, McAuley JH
J Clin Epidemiol. 2020 Aug; 124:149-159.
PMID: 31816418.


Systematic-reviews of analgesics for low back pain generally include published data only. Obtaining data from unpublished trials is potentially important because they may impact effect sizes in meta-analyses. We determined whether including unpublished data from trial registries changes the effect sizes in meta-analyses of analgesics for low back pain.