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Papers of the Week

Papers: 30 Nov 2019 - 6 Dec 2019

Human Studies

2020 Jan

Clin J Pain



Less Severe Preoperative Synovitis is Associated With Higher Self-reported Pain Intensity 12 Months After Total Knee Arthroplasty-An Exploratory Prospective Observational Study.


Petersen KK, Arendt-Nielsen L, Vela J, Skou ST, Eld M, Al-Mashkur NM, Boesen M, Riis R G, Simonsen O
Clin J Pain. 2020 Jan; 36(1):34-40.
PMID: 31794440.


Synovitis is one of the possible pain generators in osteoarthritis (OA) and is associated with upregulation of proinflammatory cytokines, which can lead to worsening of the postoperative pain. This exploratory study aimed to investigate the association between perioperative synovitis and self-reported pain 12 months after total knee arthroplasty (TKA) in patients with OA.