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Papers of the Week


2019 Nov 28


Trials


20


1

Safety and efficacy of PG102P for the control of pruritus in patients undergoing hemodialysis (SNUG trial): study protocol for a randomized controlled trial.

Authors

Kim Y C, Park J Y, Oh S, Cho J-H, Chang J H, Choi D E, Park J T, Lee J P, Kim S J, Kim D K, Ryu D-R, Lim C S
Trials. 2019 Nov 28; 20(1):651.
PMID: 31779697.

Abstract

Pruritus in patients undergoing hemodialysis is a highly prevalent complication that affects quality of life. Several medications are currently used for the treatment of uremic pruritus, but these are not satisfactory. PG102P, which is prepared from Actinidia arguta, has an immune-modulating effect on pruritus. This trial is designed to assess the antipruritic effect of PG102P compared with placebo.