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Papers of the Week

Papers: 16 Nov 2019 - 22 Nov 2019

Human Studies, Pharmacology/Drug Development

2020 Mar

Eur J Pain



Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled study.


Czarnetzki C, Desmeules J, Tessitore E, Faundez A, Chabert J, Daali Y, Fournier R, Dupuis-Lozeron E, Cedraschi C, Richard Tramèr M
Eur J Pain. 2020 Mar; 24(3):555-567.
PMID: 31743533.


Chronic pain after major lower back surgery is frequent. We investigated in adults the effect of perioperative low-dose ketamine on neuropathic lower back pain, assessed by the DN4 questionnaire, six and 12 months after major lower back surgery.