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Papers of the Week

2019 Oct

J Dent Anesth Pain Med



Anti-inflammatory effect of remifentanil in lipopolysaccharide-stimulated amniotic epithelial cells.


Kim C-H, Jeong S S, Park S J, Choi E-J, Kim Y H, Ahn J-H
J Dent Anesth Pain Med. 2019 Oct; 19(5):253-260.
PMID: 31723665.


Sometimes general anesthesia is required for dental surgery in pregnant women. Facial bone fractures or neck abscess should be treated immediately. Dental surgery, however, creates a stressful situation that can cause inflammation. Inflammatory responses are a well-known major cause of preterm labor and preterm birth. Here we demonstrate the effects of remifentanil on the factors related to preterm labor and its mechanism of action on amniotic-derived epithelial cells (WISH cells).