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Papers of the Week

Papers: 26 Oct 2019 - 1 Nov 2019

Pharmacology/Drug Development

2020 Feb

Eur J Pain



Efficacy and harms of long-term opioid therapy in chronic non-cancer pain: Systematic review and meta-analysis of open-label extension trials with a study duration ≥ 26 weeks.


This updated systematic review evaluated the efficacy, acceptability and safety of long-term opioid therapy (LTOT) for chronic non-cancer pain (CNCP).