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Papers of the Week

Papers: 26 Oct 2019 - 1 Nov 2019

Animal Studies, Pharmacology/Drug Development

2020 Mar

Br J Pharmacol



Editor's Pick

Mu and delta opioid receptors play opposite nociceptive and behavioural roles on nerve-injured mice.


Martínez-Navarro M, Cabañero D, Wawrzczak-Bargiela A, Robe A, Gavériaux-Ruff C, Kieffer BL, Przewlocki R, Baños JE, Maldonado R
Br J Pharmacol. 2020 Mar; 177(5):1187-1205.
PMID: 31655493.


Mu and delta opioid receptors (MOP, DOP) limit pain perception in physiological conditions, but their relative contribution to the manifestations of pathological pain is not completely understood. Here we used a genetic approach to investigate the opioid mechanisms modulating neuropathic pain and its comorbid manifestations.