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Papers of the Week

Papers: 19 Oct 2019 - 25 Oct 2019

Animal Studies, Pharmacology/Drug Development

2019 Oct 22

J Transl Med



Tibial post fracture pain is reduced in kinin receptors deficient mice and blunted by kinin receptor antagonists.


Minville V, Mouledous L, Jaafar A, Couture R, Brouchet A, Frances B, Tack I, Girolami J-P
J Transl Med. 2019 Oct 22; 17(1):346.
PMID: 31640792.


Tibial fracture is associated with inflammatory reaction leading to severe pain syndrome. Bradykinin receptor activation is involved in inflammatory reactions, but has never been investigated in fracture pain.