Browse by Audience
Skip to content
Papers of the Week
Minocycline Reduces Chemoradiation-Related Symptom Burden in Patients with Non-small Cell Lung Cancer: A Phase II Randomized Trial.
Abstract
In patients with non-small cell lung cancer (NSCLC), concurrent chemoradiation therapy (CRT) exacerbates a cluster of difficult-to-manage symptoms, especially cancer-related fatigue. Minocycline is a readily available, low-cost antibiotic with anti-inflammatory properties. We conducted a phase II randomized, double-blinded, placebo-controlled trial to investigate the effect of minocycline in reducing CRT-symptom burden in NSCLC.