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Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial.
Bråten L C H, Rolfsen M P, Espeland A, Wigemyr M, Aßmus J, Froholdt A, Julsrud Haugen A, Marchand G H, Kristoffersen P M, Lutro O, Randen S, Wilhelmsen M, Winsvold B S, Kadar T I, Holmgard T E, Vigeland M D, Vetti N, Nygaard Ø P, Lie B A, Hellum C, et al.
To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes).