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Papers of the Week

Papers: 12 Oct 2019 - 18 Oct 2019

Human Studies

2019 10 16



Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial.


Bråten L C H, Rolfsen M P, Espeland A, Wigemyr M, Aßmus J, Froholdt A, Julsrud Haugen A, Marchand G H, Kristoffersen P M, Lutro O, Randen S, Wilhelmsen M, Winsvold B S, Kadar T I, Holmgard T E, Vigeland M D, Vetti N, Nygaard Ø P, Lie B A, Hellum C, et al.
BMJ. 2019 10 16; 367:l5654.
PMID: 31619437.


To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes).