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Papers of the Week

2019 Oct

Niger J Clin Pract



Roles of UGT2B7 C802T gene polymorphism on the efficacy of morphine treatment on cancer pain among the Chinese han population.


Ning M, Tao Y, Hu X, Guo L, Ni J, Hu J, Shen H, Chen Y
Niger J Clin Pract. 2019 Oct; 22(10):1319-1323.
PMID: 31607718.


Morphine is a common analgesic often used to manage chronic pain, especially for patients with pain due to malignancies. Since UGT2B7 plays an important role in the metabolism of morphine, UGT2B7 gene mutation may influence the efficacy of morphine in patients with cancer being treated by this medication.