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Papers of the Week
Oswestry Disability Index scores correlate with MRI measurements in degenerating intervertebral discs and endplates.
Abstract
Low back pain (LBP) is a widespread problem and the leading cause of disability worldwide. While the cause of LBP is multifactorial, several studies suggested that inflammatory mediators in damaged subchondral plates of degenerating discs may lead to chemical sensitization and mechanical stimulation, eventually causing pain. The goal of this study was to explore associations between such changes and LBP related disability using Dynamic Contrast Enhanced MRI.