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Papers of the Week

2019 Sep

Iran J Med Sci



An Experimental Study on Spinal Cord µ-Opioid and α2-Adrenergic Receptors mRNA Expression Following Stress-Induced Hyperalgesia in Male Rats.


Hormozi A, Zarifkar A, Rostami B, Naghibalhossaini F
Iran J Med Sci. 2019 Sep; 44(5):397-405.
PMID: 31582864.


Intense stress can change pain perception and induce hyperalgesia; a phenomenon called stress-induced hyperalgesia (SIH). However, the neurobiological mechanism of this effect remains unclear. The present study aimed to investigate the effect of the spinal cord µ-opioid receptors (MOR) and α2-adrenergic receptors (α2-AR) on pain sensation in rats with SIH.