I am a
Home I AM A Search Login

Papers of the Week

Papers: 28 Sep 2019 - 4 Oct 2019

Animal Studies


J Pain Res


Inhibition of chemokine CX3CL1 in spinal cord mediates the electroacupuncture-induced suppression of inflammatory pain.


Li Y, Fang Z, Gu N, Bai F, Ma Y, Dong H, Yang Q, Xiong L
J Pain Res. 2019; 12:2663-2672.
PMID: 31564958.


Chemokine CX3CL1 and its receptor CX3CR1 in the lumbar spinal cord play crucial roles in pain processing. Electroacupuncture (EA) is recognized as an alternative therapy in pain treatment due to its efficacy and safety. However, the analgesic mechanism of EA remains unclear. The aim of this study was to investigate whether EA suppressed complete Freund's adjuvant (CFA)-induced pain via modulating CX3CL1-CX3CR1 pathway.