I am a
Home I AM A Search Login

Papers of the Week

Papers: 21 Sep 2019 - 27 Sep 2019

Human Studies

2019 Oct 29

J Rehabil Med



Unaltered low nerve growth factor and high brain-derived neurotrophic factor levels in plasma from patients with fibromyalgia after a 15-week progressive resistance exercise.


Jablochkova A, Bäckryd E, Kosek E, Mannerkorpi K, Ernberg M, Gerdle B, Ghafouri B
J Rehabil Med. 2019 Oct 29; 51(10):779-787.
PMID: 31544950.


The pathophysiology of fibromyalgia includes central and peripheral factors. Neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor, are involved in peripheral and central nervous system development of pain and hyperalgesia. Few studies have examined circulating nerve growth factor and brain-derived neurotrophic factor in fibromyalgia or have investigated whether exercise interventions affect the levels of these peptides.