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Papers of the Week
Plasma tryptophan and kynurenine in females with temporomandibular disorders and fibromyalgia – An exploratory pilot study.
Abstract
Both temporomandibular disorders myalgia (TMDM) and fibromyalgia (FM) have been linked to central and peripheral changes in serotonin availability. The precursor of serotonin, tryptophan (TRP), is mainly catabolized via another pathway to produce kynurenine (KYN), but whether changes of this pathway are present in TMDM and FM are still unclear.