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Papers of the Week


J Immunol Res


Infiltration of Blood-Derived Macrophages Contributes to the Development of Diabetic Neuropathy.


Sun J-J, Tang L, Zhao X-P, Xu J-M, Xiao Y, Li H
J Immunol Res. 2019; 2019:7597382.
PMID: 31534976.


Diabetic neuropathic pain (DNP) is a common complication associated with diabetes. Currently, its underlying pathomechanism remains unknown. Studies have revealed that the recruitment of blood monocyte-derived macrophages (MDMs) to the spinal cord plays a pivotal role in different models of central nervous system injury. Therefore, the present study aimed at exploring the infiltration and function of MDMs in DNP using a mice model.