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Papers of the Week

2019 Sep 11

BMC Pharmacol Toxicol



Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice.


Afridi R, Khan A U, Khalid S, Shal B, Rasheed H, Ullah M Z, Shehzad O, Kim Y S, Khan S
BMC Pharmacol Toxicol. 2019 Sep 11; 20(1):57.
PMID: 31511086.


Poncirin is flavanone derivative (isolated from Poncirus trifoliata) with known pharmacological activities such as anti-tumor, anti-osteoporotic, anti-inflammatory and anti-colitic. The present study aimed to explore the anti-allodynic and anti-hyperalgesic potentials of poncirin in murine models of inflammatory pain.