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Papers of the Week

2020 Mar 01

J Clin Endocrinol Metab



Opioids and their endocrine effects: A systematic review and meta-analysis.


de Vries F, Bruin M, Lobatto DJ, Dekkers OM, Schoones JW, van Furth WR, Pereira AM, Karavitaki N, Biermasz NR, Zamanipoor Najafabadi AH
J Clin Endocrinol Metab. 2020 Mar 01; 105(3):1020-9.
PMID: 31511863.


The increased use of opioids has resulted in an unprecedented opioid epidemic. Chronic opioid use causes hypogonadism, but its frequency, as well as the effects of opioids on other hypothalamo-pituitary-end organ hormone axes, remains unclear.