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DATE PUBLISHED: 2019 Sep 12
JOURNAL:J Clin Endocrinol Metab
PUBMED: http://www.ncbi.nlm.nih.gov/pubmed/31511870?dopt=Abstract
The increased use of opioids has resulted in an unprecedented opioid epidemic. Chronic opioid use causes hypogonadism, but its frequency, as well as the effects of opioids on other hypothalamo-pituitary-end organ hormone axes, remains unclear.