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Papers of the Week

Papers: 7 Sep 2019 - 13 Sep 2019


Human Studies, Pharmacology/Drug Development

2019 Oct

Int J Behav Med



The Interaction of Alcohol Use and Cannabis Use Problems in Relation to Opioid Misuse Among Adults with Chronic Pain.


Rogers AH, Shepherd JM, Paulus DJ, Orr MF, Ditre JW, Bakhshaie J, Zvolensky MJ
Int J Behav Med. 2019 Oct; 26(5):569-575.
PMID: 31489600.


The opioid epidemic is a significant public health crisis and prescription opioids are often used to manage chronic pain, despite questionable long-term efficacy. Furthermore, co-substance (mis)use is also common among individuals with chronic pain who use opioids. Alcohol has been consistently used to manage chronic pain, partly due to its acute analgesic properties. Cannabis has also recently garnered attention in the context of pain management, though research examining its efficacy for pain has produced mixed results. Nevertheless, there is accumulating evidence that concurrent substance co-use is positively associated with use and misuse of additional substances, particularly among individuals with chronic pain. Thus, the goal of this study was to examine the main and interactive effects of alcohol use problems and cannabis use problems in relation to opioid misuse among adults with chronic pain who use opioids.