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Papers of the Week

2019 Sep

Medicine (Baltimore)



Syphilis and parvovirus B19 co-infection imitating a lupus nephropathy: A case report.


Jaunin E, Kissling S, Rotman S, Waeber G, Halfon M
Medicine (Baltimore). 2019 Sep; 98(36):e17040.
PMID: 31490394.


Syphilis can share clinical features with autoimmune diseases, such as cutaneous Lupus or rheumatoid arthritis. Moreover, secondary syphilis can have visceral involvement, thus affecting the kidney. Syphilitic nephropathy causes nephrotic syndrome with a classic membranous pattern. We present a unique presentation of a co-infection by syphilis and parvovirus B19 sharing all the biological and histological features of proliferative lupus nephritis (LN).