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Papers of the Week

2019 Sep 06

J Neurosurg Spine

Relationship among anesthesia technique, surgical stress, and cognitive dysfunction following spinal surgery: a randomized trial.


Ezhevskaya AA, Ovechkin AM, Prusakova ZB, Zagrekov VI, Mlyavykh SG, Anderson GD
J Neurosurg Spine. 2019 Sep 06:1-8.
PMID: 31491757.


Surgical trauma is known to result in systemic inflammatory changes that can lead to postoperative cognitive dysfunction. In the present study, the authors compared the effects of an epidural anesthesia protocol to those of traditional anesthesia with regard to postoperative inflammatory changes, cellular immunity, and cognitive dysfunction.