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Papers of the Week

2019 Sep 01

J Clin Med



Pregabalin Failed to Prevent Dry Eye Symptoms after Laser-Assisted in Situ Keratomileusis (LASIK) in a Randomized Pilot Study.


Galor A, Patel S, Small LR, Rodriguez A, Venincasa MJ, Valido SE, Feuer W, Levitt RC, Sarantopoulos CD, Felix ER
J Clin Med. 2019 Sep 01; 8(9).
PMID: 31480601.


Perioperative pregabalin administration has been found to reduce the risk of persistent pain after a variety of surgical procedures. However, this approach has not been tested in relation to eye surgery. As such, the purpose of this study was to evaluate whether perioperative pregabalin can reduce the presence of dry eye (DE) symptoms, including eye pain, six months after laser-assisted in situ keratomileusis (LASIK).