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Papers of the Week

Papers: 31 Aug 2019 - 6 Sep 2019

Human Studies

2020 Jul




Patient-Specific Analysis of Neural Activation During Spinal Cord Stimulation for Pain.


Lempka SF, Zander HJ, Anaya CJ, Wyant A, Ozinga JG, Machado AG
Neuromodulation. 2020 Jul; 23(5):572-581.
PMID: 31464040.


Despite the widespread use of spinal cord stimulation (SCS) for chronic pain management, its neuromodulatory effects remain poorly understood. Computational models provide a valuable tool to study SCS and its effects on axonal pathways within the spinal cord. However, these models must include sufficient detail to correlate model predictions with clinical effects, including patient-specific data. Therefore, the goal of this study was to investigate axonal activation at clinically relevant SCS parameters using a computer model that incorporated patient-specific anatomy and electrode locations.