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Papers of the Week

2019 Jul




Perinatal Pyogenic Liver Abscess: A Rare Entity and First Reported Case of .


Schmiedecke SS, Napolitano PG, Estrada SM
AJP Rep. 2019 Jul; 9(3):e251-e255.
PMID: 31435485.


 Pyogenic liver abscess (PLA) is a rare clinical entity, occurring in ∼2.3 per 100,000 patients. Perinatal PLA syndromes are exceedingly rare with just seven previously described cases in the literature and no prior Klebsiella-associated reports.  A 29-year-old gravida 2 para 1 woman at 11 weeks gestation reporting fever, body aches, and headache. Search for an infectious source identified a 4-cm liver abscess. Percutaneous drainage confirmed infection. The patient was treated with antibiotics until imaging verified complete resolution of the abscess.  PLA is an uncommon etiology of sepsis in pregnancy. A thorough workup until a source was identified resulted in accurate diagnosis. This allowed for directed therapy and prompt recovery, undoubtedly contributing to favorable pregnancy outcomes in this first report of Klebsiella-associated perinatal PLA.