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Papers of the Week

Papers: 10 Aug 2019 - 16 Aug 2019

Animal Studies, Human Studies

2020 Mar 01

Rheumatology (Oxford)



Human osteoarthritic synovial fluid increases excitability of mouse dorsal root ganglion sensory neurons: an in-vitro translational model to study arthritic pain.



Knee OA is a leading global cause of morbidity. This study investigates the effects of knee SF from patients with OA on the activity of dorsal root ganglion sensory neurons that innervate the knee (knee neurons) as a novel translational model of disease-mediated nociception in human OA.