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Papers of the Week

Papers: 3 Aug 2019 - 9 Aug 2019

Human Studies

2020 Jan

Arthritis Rheumatol



Inflammation is associated with pro-nociceptive brain connections in rheumatoid arthritis patients with concomitant fibromyalgia.


Kaplan CM, Schrepf A, Ichesco E, Larkin T, Harte SE, Harris RE, Murray AD, Waiter GD, Clauw DJ, Basu N
Arthritis Rheumatol. 2020 Jan; 72(1):41-46.
PMID: 31379121.


Rheumatoid arthritis (RA) patients with comorbid fibromyalgia (FM) manifest alterations in brain connectivity synonymous with central sensitization. Here we consider how peripheral inflammation, the principal nociceptive stimulus in RA, interacts with brain connectivity in RA patients with comorbid FM.