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Papers of the Week

2019 Oct 28

J Ethnopharmacol


Ameliorative influence of cnestis ferruginea vahl ex DC (connaraceae) root extract on kainic acid-induced temporal lobe epilepsy in mice: Role of oxidative stress and neuroinflammation.


Ojo E, Ishola IO, Ben-Azu B, Afolayan O, James AB, Ajayi AM, Umukoro S, Adeyemi O
J Ethnopharmacol. 2019 Oct 28; 243:112117.
PMID: 31351192.


ETHNOPHARMACOLOGY RELEVANCE: the root decoction of Cnestis ferruginea Vahl ex DC (Connaraceae) is widely used in traditional African medicine for the treatment of various ailments including pain, inflammation and epilepsy. We have earlier reported anticonvulsant effect of Cnestis ferruginea root extract in mice.