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Treatment-induced neuropathy of diabetes is an acute small-fibre neuropathy affecting people with poorly controlled diabetes who experience a rapid improvement in glycaemic control within the setting of chronic hyperglycaemia. The disease can present with severe and poorly responsive neuropathic pain, symptoms of autonomic dysfunction, or a combination of both Moreover, a high incidence of associated microvascular disease, such as rapid progression of retinopathy, has been reported in affected individuals. This article is protected by copyright. All rights reserved.