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Papers of the Week

2020 Mar

Clin Exp Dermatol



Cholinergic Pruritus responding to Omalizumab: a case report.


Hasan SB, Ali FM, Ingram JR
Clin Exp Dermatol. 2020 Mar; 45(2):264-266.
PMID: 31323131.


Cholinergic pruritus is a rare condition characterised by generalised itch provoked by sweating without an associated rash. It is exacerbated by heat, exercise, emotion or activities of daily living.(1) The pruritus can be severe and have a considerable impact on the patient's life. A 60 year old gentleman presented to our clinic in 2012 with a 9-month history of severe pruritus and a burning sensation that was induced by exercise and heat and relieved by cooling. The symptoms were not associated with a skin rash. His Dermatology Life Quality Index (DLQI) score of 23/30 indicated an extremely large effect on his quality of life. This article is protected by copyright. All rights reserved.