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Papers of the Week

Papers: 13 Jul 2019 - 19 Jul 2019

Human Studies


J Pain Res


Recruitment and inclusion procedures as “pain killers” in clinical trials?


Nothnagel H, Brown Menard M, Kvarstein G, Norheim AJ, Weiss T, Puta C, Mist SD, Musial F
J Pain Res. 2019; 12:2027-2037.
PMID: 31308731.


Recruitment and inclusion procedures in clinical trials are time critical. This holds particularly true for studies investigating patients with fluctuating symptom patterns, like those with chronic neck pain. In a feasibility study on neck pain, we found a clinically relevant decrease in pain ratings within the recruitment period. This paper analyses the phenomenon and gives recommendations for recruitment procedures in clinical trials on pain.