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Papers of the Week

2020 Jan 01

Rheumatology (Oxford)



Monosodium urate crystal interleukin-1β release is dependent on Toll-like receptor 4 and transient receptor potential V1 activation.


Rossato MF, Hoffmeister C, Trevisan G, Bezerra F, Cunha TM, Ferreira J, Silva CR
Rheumatology (Oxford). 2020 Jan 01; 59(1):233-242.
PMID: 31298290.


The present study aimed to elucidate the mechanisms involved in MSU-induced IL-1β release in a rodent animal model of acute gout arthritis.