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Papers of the Week

Papers: 29 Jun 2019 - 5 Jul 2019

Human Studies


2019 Sep

Can J Neurol Sci



Genetic Analysis of a Large Family with Migraine, Vertigo, and Motion Sickness.


Peddareddygari L R, Kramer PD, Hanna PA, Levenstien MA, Grewal RP
Can J Neurol Sci. 2019 Sep; 46(5):512-517.
PMID: 31258098.


Migraine is a common disorder most typically presenting as headache and often associated with vertigo and motion sickness. It is a genetically complex condition with multiple genes ultimately contributing to the predisposition and development of this episodic neurological disorder. We identified a large American family of 29 individuals of which 17 members suffered from at least one of these disorders, migraine, vertigo, or motion sickness. Many of these individuals suffered from several simultaneously. We hypothesized that vertigo and motion sickness may involve genes that are independent to those directly contributing to migraine susceptibility.