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Papers of the Week


2019 Oct


Vasc Endovascular Surg


53


7

Prognostic Role of Admission C-Reactive Protein Level as a Predictor of In-Hospital Mortality in Type-A Acute Aortic Dissection: A Meta-Analysis.

Authors

Hsieh W C, Henry B M, Hsieh C C, Maruna P, Omara M, Lindner J
Vasc Endovascular Surg. 2019 Oct; 53(7):547-557.
PMID: 31248351.

Abstract

Acute aortic dissection (AD) is a lethal vascular disease, accounting for over 90% cases of acute aortic syndrome. Despite advances in understanding associated risk factors, the long-term prognosis for AD patients is still poor. Several prognostic biomarkers have been used for AD as per the IRAD, such as older age (>70 years), onset of chest pain and hypotension, but they are not effective in all patients. Instead, C-reactive protein (CRP) is a consistent inflammatory marker. CRP levels are abnormally increased in AD. However, the prognostic value of serum CRP level in AD remains unclear.