I am a
Home I AM A Search Login

Papers of the Week

Papers: 29 Jun 2019 - 5 Jul 2019

Human Studies

2019 Oct

Eur J Pain



A new experimental model of muscle pain in humans based on short-wave diathermy.


Mista CA, Laugero S, Adur J, Andersen OK, Biurrun Manresa JA
Eur J Pain. 2019 Oct; 23(9):1733-1742.
PMID: 31251430.


Experimental models of pain in humans are crucial for understanding pain mechanisms. The most often used muscle pain models involve the injection of algesic substances, such as hypertonic saline solution or nerve growth factor, or the induction of delayed onset muscle soreness (DOMS) by an unaccustomed exercise routine. However, these models are either invasive or take substantial time to develop, and the elicited level of pain/soreness is difficult to control. To overcome these shortcomings, we propose to elicit muscle pain by a localized application of short-wave diathermy (SWD).