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Papers of the Week

2019 Aug




Preadmission Statin Use and 90-day Mortality in the Critically Ill: A Retrospective Association Study.


Oh T K, Song I-A, Lee J H, Lim C, Jeon Y-T, Bae H-J, Jo Y H, Jee H-J
Anesthesiology. 2019 Aug; 131(2):315-327.
PMID: 31246609.


Randomized controlled trials evaluating the potential value of statin administration for intensive care unit patients have not observed a benefitHowever, the chronic preadmission use of statins among patients admitted to the intensive care unit has not been robustly studied WHAT THIS ARTICLE TELLS US THAT IS NEW: Single-center retrospective data suggest that preadmission statin use may be associated with decreased 90-day mortality among some intensive care unit patientsSpecific statin agents and noncardiovascular mortality may demonstrate a stronger signal for further study BACKGROUND:: This study aimed to examine the association between preadmission statin use and 90-day mortality in critically ill patients and to investigate whether this association differed according to statin type and dose. We hypothesized that preadmission statin use was associated with lower 90-day mortality.