I am a
Home I AM A Search Login

Papers of the Week

2019 Jun 20

Cochrane Database Syst Rev



Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn’s disease.


Gjuladin-Hellon T, Gordon M, Iheozor-Ejiofor Z, Akobeng AK
Cochrane Database Syst Rev. 2019 Jun 20; 6(6):CD008414.
PMID: 31220875.


Crohn's disease (CD) is a chronic inflammatory disorder that can involve any part of the gastrointestinal tract. 5-Aminosalicylates (5-ASAs) are locally acting, anti-inflammatory compounds that reduce inflammation of the colonic mucosa with release profiles that vary among various commercially available formulations. This updated Cochrane review summarizes current evidence on the use of 5-ASA formulations for maintenance of surgically-induced remission in CD.