Papers of the Week

Single-dose mebendazole is widely used in preventive chemotherapy against the soil-transmitted helminths (STHs) , hookworm and , yet it shows limited efficacy against hookworm and infections. The use of adapted treatment regimens might provide a strategy to control and eliminate STH infections in STH-persistent settings. We evaluated the safety and efficacy of the multiple dose mebendazole regimen (3 days 100 mg bid) a single dose of 500 mg mebendazole in a setting with high STH prevalence and high drug pressure.