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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Pulsed radiofrequency to the dorsal root ganglion or the sciatic nerve reduces neuropathic pain behavior, decreases peripheral pro-inflammatory cytokines and spinal β-catenin in chronic constriction injury rats.

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2019 May 14


Reg Anesth Pain Med


http://www.ncbi.nlm.nih.gov/pubmed/31092705?dopt=Abstract

Pulsed radiofrequency to the dorsal root ganglion or the sciatic nerve reduces neuropathic pain behavior, decreases peripheral pro-inflammatory cytokines and spinal β-catenin in chronic constriction injury rats.

Authors

Pulsed radiofrequency to the dorsal root ganglion or the sciatic nerve reduces neuropathic pain behavior, decreases peripheral pro-inflammatory cytokines and spinal β-catenin in chronic constriction injury rats.
Jiang R, Li P, Yao Y-X, Li H, Liu R, Huang L-E, Ling S, Peng Z, Yang J, Zha L, Xia L-P, Chen X, Feng Z
Reg Anesth Pain Med. 2019 May 14.
PMID: 31092705.

Abstract

Pulsed radiofrequency (PRF) is a minimal neurodestructive interventional pain therapy. However, its analgesic mechanism remains largely unclear. We aimed to investigate the peripheral and spinal mechanisms of PRF applied either adjacent to the ipsilateral L5 dorsal root ganglion (PRF-DRG) or PRF to the sciatic nerve (PRF-SN) in the neuropathic pain behavior induced by chronic constriction injury (CCI) in rats.
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