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Papers of the Week

2020 Feb

World J Urol



Management of Peyronie’s disease with collagenase Clostridium histolyticum in the acute phase.


El-Khatib FM, Towe M, Yafi FA
World J Urol. 2020 Feb; 38(2):299-304.
PMID: 31093703.


Peyronie's disease (PD) can affect men of all ages and is associated with penile pain as well as curvature and erectile dysfunction. Treatment modalities for PD include conservative, less invasive and surgical treatments. Choice of treatment depends on the disease's phase. Injection of collagenase Clostridium histolyticum (CCH) is only the Food and Drug Administration approved treatment for the management of the chronic phase of the disease. Only a few limited studies have evaluated its potential benefits during the acute phase.