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Papers of the Week

Papers: 18 May 2019 - 24 May 2019

Animal Studies

2019 Jun

Clin Orthop Relat Res



Development and Characterization of a Novel Bipedal Standing Mouse Model of Intervertebral Disc and Facet Joint Degeneration.


Gao X, Wang L, Shao Y, Chen X, Zhang J, Chu J, Jiang T, Zhang Z, Huang M
Clin Orthop Relat Res. 2019 Jun; 477(6):1492-1504.
PMID: 31094848.


Intervertebral disc degeneration is a major cause of chronic low back pain, and excessive loading contributes to intervertebral disc degeneration. However, the lack of an effective bipedal in vivo animal model limits research about this condition.