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Papers of the Week

2019 May

Medicine (Baltimore)



Intranasal lidocaine for acute migraine: A protocol for the systematic review of randomized clinical trials.


Chi P-W, Hsieh K-Y, Tsai C-W, Hsu C-W, Bai C-H, Chen C, Hsu Y-P
Medicine (Baltimore). 2019 May; 98(20):e15699.
PMID: 31096514.


Intranasal lidocaine has been shown to be effective in treating patients with acute migraines; however, its efficacy is still controversial. The aim of our study is to assess the efficacy and safety of intranasal lidocaine compared with a placebo or an active comparator for the treatment of acute migraine.