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Papers of the Week

Papers: 11 May 2019 - 17 May 2019

Human Studies


2019 Oct

J Periodontol



Periodontal inflammation is related to increased serum calcitonin gene-related peptide (CGRP) levels in patients with chronic migraine.


Leira Y, Ameijeira P, Domínguez C, López-Arias E, Ávila P, Pérez-Mato M, Sobrino T, Campos F, D'Aiuto F, Leira R, Blanco J
J Periodontol. 2019 Oct; 90(10):1088-1095.
PMID: 31070784.


Recently, a relationship was found between periodontitis and chronic migraine. Calcitonin gene-related peptide (CGRP) is a key element in migraine pathophysiology. However, no information exists of the potential association between periodontal inflammation and CGRP in chronic migraine. The aim of the study was, therefore, to investigate whether there is a link between periodontitis and peripheral levels of CGRP in a cohort of patients with chronic migraine.