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Papers: 4 May 2019 - 10 May 2019
Human Studies, Pharmacology/Drug Development
2019 Jul 01
Drug Alcohol Depend
200
Chronic opiate use leads to a sensitized behavioral response to acute pain, which in turn, leads to escalating doses of opiates. This study was designed to test the hypothesis that chronic opiate usage is also associated with a sensitized neurobiological response to acute pain in individuals that have used prescription opiates for 6 or more months.